Susan lindquist lab

Sometimes it’s the littlest things that matter most. Take for instance the structure of proteins packed inside cells. Thanks to the work of Susan Lee Lindquist we not only appreciate the impact of the origami-­like ways in which proteins are folded­­–we know that harnessing that power has applications in everything from evolution to human disease treatments to biomaterials.

Inside every cell, DNA carries the instructions that tell proteins–­­the workhorses of cells­­–how to do their jobs. Each protein must be folded in a very specific way in order to carry out its assigned function and when that process goes wrong, and the proteins don’t fold correctly, it can have terrible consequences.

Cystic fibrosis, Alzheimer’s, Parkinson’s, and many other diseases are a result of misshapen proteins wreaking havoc inside the body. Lindquist’s groundbreaking and imaginative experiments have succeeded in reproducing many of the consequences of Parkinson’s in yeast cells­­–an accomplishment that may yield new and much more effective drugs to treat the devastating diseas

Susan Lindquist

American geneticist

Susan Lee Lindquist, ForMemRS (June 5, 1949 – October 27, 2016) was an American professor of biology at MIT[4][5] specializing in molecular biology, particularly the protein folding problem[3][6] within a family of molecules known as heat-shock proteins,[7][8] and prions.[9] Lindquist was a member and former director of the Whitehead Institute and was awarded the National Medal of Science in 2010.[10][11][12]

Early life and education

Lindquist was born in Chicago, Illinois, to Iver and Eleanor (née Maggio), and attended Maine South High School in Park Ridge.[13]

Lindquist's father and mother were of Swedish and Italian descent, respectively,[14] and although they expected her to become a housewife,[15] Susan studied microbiology at the University of Illinois as an undergraduate and received her PhD in biology from Harvard University in 1976.[16] She completed a post-doctoral fellowship at th

Susan Lindquist, pioneering biologist and former director of Whitehead Institute, dies at 67

MIT Professor Susan Lee Lindquist, a member and former director of the Whitehead Institute, and one of the nation’s most lauded scientists, yesterday succumbed to cancer at age 67. Her nearly 40-year career was defined by intellectually courageous, boundary-defying research and a passion for nurturing new generations of scientific talent.

“Sue has meant so much to Whitehead as an institution of science, and as a community of scientists, and her passing leaves us diminished in so many ways,” reflects David C. Page, director of Whitehead Institute and a professor of biology at MIT. “She was a risk-taker and an innovator. She believed that if we were not reaching for things beyond our grasp, we were not doing our job as researchers; if we were not constantly striving for that which we could only imagine, we were not fulfilling our obligations to society as scientists.”

A cornerstone of the Whitehead Institute community, a professor of biology at MIT, and a Howard Hughes Medical Instit

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